/* ============ HNSCope Atlas Browser — design system ============ */
:root{
  --bg:#0a0e17; --bg2:#0e1422; --panel:#121a2b; --panel2:#172138;
  --line:#1f2c45; --line2:#2a3a5a;
  --txt:#e7edf7; --txt-dim:#9fb0c9; --txt-mute:#647394;
  --accent:#22d3ee; --accent2:#6366f1; --magenta:#ec4899; --amber:#f59e0b;
  --good:#34d399; --bad:#f87171;
  --shadow:0 8px 30px rgba(0,0,0,.45);
  --r:12px; --r-sm:8px;
  --font:'Inter',-apple-system,BlinkMacSystemFont,'Segoe UI',Roboto,sans-serif;
  --mono:'SF Mono',ui-monospace,'JetBrains Mono',Menlo,monospace;
}
*{box-sizing:border-box;margin:0;padding:0}
html,body{height:100%}
body{font-family:var(--font);background:var(--bg);color:var(--txt);font-size:14px;
  -webkit-font-smoothing:antialiased;overflow:hidden}
#app{display:grid;grid-template-columns:208px 1fr;height:100vh}

/* ---------- sidebar ---------- */
#nav{background:linear-gradient(180deg,var(--bg2),var(--bg));border-right:1px solid var(--line);
  display:flex;flex-direction:column;padding:18px 14px}
.brand{display:flex;align-items:center;gap:11px;margin-bottom:26px;padding:0 4px}
.brand-mark{width:34px;height:34px;border-radius:10px;
  background:radial-gradient(circle at 32% 30%,var(--accent),var(--accent2) 70%);
  box-shadow:0 0 18px rgba(34,211,238,.5);position:relative}
.brand-mark::after{content:"";position:absolute;inset:11px;border-radius:50%;background:var(--bg)}
.brand-name{font-weight:800;font-size:17px;letter-spacing:.3px}
.brand-sub{font-size:11px;color:var(--txt-mute);letter-spacing:.5px;text-transform:uppercase}
.nav-items{display:flex;flex-direction:column;gap:4px}
.nav-btn{display:flex;align-items:center;gap:11px;background:none;border:none;color:var(--txt-dim);
  font:inherit;font-weight:600;padding:10px 12px;border-radius:var(--r-sm);cursor:pointer;
  text-align:left;transition:.15s;width:100%}
.nav-btn .ni{font-size:15px;width:18px;text-align:center;opacity:.8}
.nav-btn:hover{background:var(--panel);color:var(--txt)}
.nav-btn.active{background:linear-gradient(90deg,rgba(34,211,238,.16),rgba(99,102,241,.10));
  color:#fff;box-shadow:inset 2px 0 0 var(--accent)}
.nav-foot{margin-top:auto;padding-top:16px}
.mini-stats{font-size:11.5px;color:var(--txt-dim);line-height:1.7;background:var(--panel);
  border:1px solid var(--line);border-radius:var(--r-sm);padding:10px 12px;margin-bottom:12px}
.mini-stats b{color:var(--accent);font-variant-numeric:tabular-nums}
.nav-credit{font-size:10.5px;color:var(--txt-mute);line-height:1.5;text-align:center}

/* ---------- main / views ---------- */
#main{position:relative;overflow:hidden;display:flex;flex-direction:column}
.view{display:none;flex-direction:column;height:100%;overflow:hidden}
.view.active{display:flex}

/* ---------- topbar ---------- */
.topbar{display:flex;align-items:flex-end;gap:16px;padding:14px 20px;
  background:var(--bg2);border-bottom:1px solid var(--line);flex-wrap:wrap}
.tb-group{display:flex;flex-direction:column;gap:5px;min-width:140px}
.tb-group.grow{flex:1;min-width:220px}
.tb-label{font-size:10.5px;text-transform:uppercase;letter-spacing:.6px;color:var(--txt-mute);font-weight:700}
.select,.input{background:var(--panel);border:1px solid var(--line2);color:var(--txt);
  border-radius:var(--r-sm);padding:8px 11px;font:inherit;font-size:13px;outline:none;transition:.15s;width:100%}
.select:focus,.input:focus{border-color:var(--accent);box-shadow:0 0 0 3px rgba(34,211,238,.12)}
.select{cursor:pointer;appearance:none;
  background-image:url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' width='10' height='6' viewBox='0 0 10 6'%3E%3Cpath d='M1 1l4 4 4-4' stroke='%239fb0c9' stroke-width='1.5' fill='none'/%3E%3C/svg%3E");
  background-repeat:no-repeat;background-position:right 11px center;padding-right:28px}
.gene-search{position:relative}
.suggest{position:absolute;top:calc(100% + 4px);left:0;right:0;background:var(--panel2);
  border:1px solid var(--line2);border-radius:var(--r-sm);box-shadow:var(--shadow);z-index:30;
  max-height:280px;overflow:auto}
.suggest div{padding:8px 12px;cursor:pointer;font-size:13px;font-family:var(--mono)}
.suggest div:hover,.suggest div.sel{background:rgba(34,211,238,.14);color:#fff}
.hidden{display:none!important}

.btn{background:var(--panel);border:1px solid var(--line2);color:var(--txt);font:inherit;font-weight:600;
  padding:8px 14px;border-radius:var(--r-sm);cursor:pointer;transition:.15s;white-space:nowrap}
.btn:hover{border-color:var(--accent);color:#fff}
.btn.primary{background:linear-gradient(90deg,var(--accent),var(--accent2));border:none;color:#06121a}
.btn.primary:hover{filter:brightness(1.08)}
.btn.ghost{background:none}

/* ---------- atlas stage ---------- */
.atlas-stage{flex:1;display:grid;grid-template-columns:1fr 232px;overflow:hidden}
#scatter-wrap{position:relative;background:
  radial-gradient(ellipse at 50% 40%,#0c1322,#080b12);overflow:hidden}
#scatter{display:block;width:100%;height:100%}
.stage-hint{position:absolute;bottom:10px;left:14px;font-size:11px;color:var(--txt-mute);
  background:rgba(8,11,18,.6);padding:4px 10px;border-radius:20px;pointer-events:none;backdrop-filter:blur(4px)}
.loading{position:absolute;inset:0;display:flex;flex-direction:column;align-items:center;justify-content:center;
  gap:16px;background:rgba(8,11,18,.82);color:var(--txt-dim);font-size:13px;z-index:20;backdrop-filter:blur(3px)}
.spinner{width:38px;height:38px;border:3px solid var(--line2);border-top-color:var(--accent);
  border-radius:50%;animation:spin 1s linear infinite}
@keyframes spin{to{transform:rotate(360deg)}}
.colorbar{position:absolute;right:14px;top:14px;width:160px;background:rgba(12,18,30,.86);
  border:1px solid var(--line2);border-radius:var(--r-sm);padding:10px 12px;font-size:11px;z-index:15;backdrop-filter:blur(6px)}
.colorbar .cb-title{font-weight:700;margin-bottom:7px;color:var(--txt)}
.colorbar .cb-grad{height:10px;border-radius:5px;margin-bottom:5px}
.colorbar .cb-scale{display:flex;justify-content:space-between;color:var(--txt-mute);font-variant-numeric:tabular-nums}
.hover-tip{position:absolute;pointer-events:none;z-index:25;background:rgba(8,11,18,.94);
  border:1px solid var(--line2);border-radius:var(--r-sm);padding:8px 11px;font-size:12px;
  box-shadow:var(--shadow);max-width:240px;line-height:1.6}
.hover-tip b{color:var(--accent)}

/* ---------- legend ---------- */
.legend{background:var(--bg2);border-left:1px solid var(--line);overflow-y:auto;padding:14px 12px}
.legend h4{font-size:11px;text-transform:uppercase;letter-spacing:.6px;color:var(--txt-mute);margin-bottom:10px}
.leg-item{display:flex;align-items:center;gap:9px;padding:5px 7px;border-radius:6px;cursor:pointer;
  font-size:12.5px;transition:.12s}
.leg-item:hover{background:var(--panel)}
.leg-item.off{opacity:.32}
.leg-swatch{width:13px;height:13px;border-radius:3px;flex-shrink:0;box-shadow:0 0 0 1px rgba(255,255,255,.12)}
.leg-name{flex:1;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
.leg-count{font-size:10.5px;color:var(--txt-mute);font-variant-numeric:tabular-nums}
.legend-actions{display:flex;gap:6px;margin-bottom:10px}
.legend-actions button{flex:1;font-size:11px;padding:5px;background:var(--panel);border:1px solid var(--line);
  color:var(--txt-dim);border-radius:6px;cursor:pointer}
.legend-actions button:hover{color:#fff;border-color:var(--accent)}

/* ---------- atlas controls ---------- */
.atlas-controls{display:flex;align-items:center;gap:22px;padding:11px 20px;background:var(--bg2);
  border-top:1px solid var(--line)}
.ctl{display:flex;align-items:center;gap:9px;font-size:12px;color:var(--txt-dim)}
.ctl input[type=range]{width:110px;accent-color:var(--accent)}
.ctl-spacer{flex:1}
.selection-info{font-size:12px;color:var(--txt-dim)}
.selection-info b{color:var(--accent);font-variant-numeric:tabular-nums}

/* ---------- generic panels / dashboards ---------- */
.panel-scroll{flex:1;overflow-y:auto;padding:22px;display:flex;flex-direction:column;gap:20px}
.kpi-row{display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));gap:14px}
.kpi{background:linear-gradient(160deg,var(--panel2),var(--panel));border:1px solid var(--line);
  border-radius:var(--r);padding:16px 18px;position:relative;overflow:hidden}
.kpi::before{content:"";position:absolute;top:0;left:0;width:3px;height:100%;background:var(--accent)}
.kpi.k2::before{background:var(--magenta)} .kpi.k3::before{background:var(--amber)} .kpi.k4::before{background:var(--good)}
.kpi-val{font-size:26px;font-weight:800;letter-spacing:-.5px;font-variant-numeric:tabular-nums}
.kpi-lbl{font-size:11.5px;color:var(--txt-mute);margin-top:3px;text-transform:uppercase;letter-spacing:.4px}
.grid-2{display:grid;grid-template-columns:repeat(auto-fit,minmax(380px,1fr));gap:18px}
.card{background:var(--panel);border:1px solid var(--line);border-radius:var(--r);padding:16px 18px}
.card h3{font-size:14px;margin-bottom:12px;font-weight:700;display:flex;gap:8px;align-items:baseline}
.muted{color:var(--txt-mute);font-weight:400;font-size:12px}
.plot{width:100%;height:300px}
.plot-area{background:var(--panel);border:1px solid var(--line);border-radius:var(--r);padding:12px;min-height:420px}
.markers-table-wrap h3{font-size:14px;margin:6px 0 12px}

/* tables */
table{width:100%;border-collapse:collapse;font-size:12.5px}
th,td{text-align:left;padding:7px 10px;border-bottom:1px solid var(--line)}
th{color:var(--txt-mute);font-weight:700;font-size:11px;text-transform:uppercase;letter-spacing:.4px;
  position:sticky;top:0;background:var(--panel)}
td{color:var(--txt-dim);font-variant-numeric:tabular-nums}
tr:hover td{color:var(--txt)}
.tbl-scroll{max-height:420px;overflow:auto}
.chip{display:inline-block;padding:2px 8px;border-radius:20px;font-size:11px;font-weight:600}
.chip.pos{background:rgba(236,72,153,.18);color:#f9a8d4}
.chip.neg{background:rgba(52,211,153,.16);color:#6ee7b7}
.chip.unk{background:rgba(100,115,148,.18);color:var(--txt-dim)}

.methods{font-size:13px;line-height:1.8;color:var(--txt-dim)}
.methods code{font-family:var(--mono);background:var(--bg);padding:2px 6px;border-radius:4px;color:var(--accent);font-size:12px}
.methods .step{display:flex;gap:10px;align-items:flex-start;padding:5px 0}
.methods .step .n{width:22px;height:22px;border-radius:50%;background:var(--panel2);border:1px solid var(--line2);
  display:flex;align-items:center;justify-content:center;font-size:11px;font-weight:700;color:var(--accent);flex-shrink:0}
.toast{position:fixed;bottom:22px;left:50%;transform:translateX(-50%);background:var(--panel2);
  border:1px solid var(--line2);color:var(--txt);padding:11px 18px;border-radius:24px;box-shadow:var(--shadow);
  z-index:99;font-size:13px;opacity:0;transition:.25s}
.toast.show{opacity:1}
.toast.err{border-color:var(--bad);color:#fecaca}
::-webkit-scrollbar{width:9px;height:9px}
::-webkit-scrollbar-thumb{background:var(--line2);border-radius:6px}
::-webkit-scrollbar-thumb:hover{background:#36496f}
::-webkit-scrollbar-track{background:transparent}